Cellular and Molecular Mechanisms of PEAK1-Mediated TGFbeta Signaling and Function
Transforming growth factor beta (TGFbeta) has well-established roles in regulating both normal physiological and pathophysiological processes. The multi-faceted effects of TGFbeta are commonly mediated by both canonical Smad2/3 signaling and a variety of non-canonical signaling pathways. While TGFbeta signaling is essential during embryogenesis and tissue homeostasis, its dysregulation can lead to aberrant fibrosis...
Project Theme:
Biomedicine